
- Episode 1 Gwen Stefani, Ben Platt, Zac Brown Band
- Episode 2 Demi Moore, Justin Hartley, Mark Ronson ft. Yebba
- Episode 3 Robert De Niro, Jameela Jamil, Bastille
- Episode 4 Michael Che & Colin Jost, Dove Cameron, Robert Irwin, Carole King
- Episode 5 Billie Eilish, Sebastian Maniscalco
- Episode 6 James Spader, Ruby Rose, Elvis Duran, DaBaby
- Episode 7 Lin-Manuel Miranda, Chris Colfer, The Cast of Freestyle Love Supreme
- Episode 8 Natalie Portman, Henry Winkler, Robbie Robertson
- Episode 9 Taylor Swift, Chris O’Dowd, Angel Olsen
- Episode 10 Joaquin Phoenix, Zoey Deutch Jimmy welcomes actor Joaquin Phoenix and actress Zoey Deutch.
- Episode 11 Edward Norton, Alessia Cara
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Episode 12
Lupita Nyong’o, Dane Cook, Jay “Sinatraa” Won, Matthew “Super” DeLisi, The Avett Brothers
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Episode 13
Clive Owen, Elsie Fisher, Lewis Capaldi
- Episode 14 Jesse Eisenberg, Hailee Steinfeld, Steve Miller
- Episode 15 Priyanka Chopra Jonas, Questlove & Tariq “Black Thought” Trotter, Rex Orange County
- Episode 16 Alec Baldwin, Kate Beckinsale, Young Thug ft. Gunna
- Episode 17 Scarlett Johansson, Pete Buttigieg, Jim James, Teddy Abrams & the Louisville Orchestra
- Episode 18 Jessica Biel, Billy Crudup, Jay Jurden
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Episode 19
Michael Douglas, Kathryn Hahn, Jenny Lewis
- Episode 20 Keegan-Michael Key, Chance the Rapper, Brockhampton
- Episode 21 John Cena, Luke Bryan
- Episode 22 Emma Thompson, Joel Kinnaman, Liam Gallagher
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Episode 23
Reese Witherspoon, Rhett & Link, Daniel Humm
- Episode 24 Emilia Clarke, Bobby Cannavale, Booker T. Jones, FKA Twigs
- Episode 25 Kristen Stewart, Gaten Matarazzo, Pete Lee
- Episode 26 Chris Evans, Naomi Scott, EarthGang
- Episode 27 Adam Sandler, Jenny Slate, Megan Gailey
- Episode 28 Henry Golding, Noomi Rapace, Dan White
- Episode 29 Matthew McConaughey, Chip & Joanna Gaines, Gucci Mane
- Episode 30 Michael Shannon, Jenna Bush Hager & Barbara Pierce Bush, Pete Yorn
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Episode 31
Kristen Bell, Judd Apatow, Danny Brown
- Episode 32 Rachel Maddow, Tony Hale, Dominic Fike
- Episode 33 Alex Rodriguez, Lili Reinhart, Ian Lara
- Episode 34 Céline Dion, Tig Notaro, Colin O’Brady, Shin Lim
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Episode 35
Seth Meyers, Cobie Smulders, Tones and I
- Episode 36 Chadwick Boseman, Evan Rachel Wood, David Byrne, American Utopia
- Episode 37 Dolly Parton, Kacey Musgraves
- Episode 38 Will Ferrell, Alan Cumming, Jessica Kirson
- Episode 39 John Legend, M. Night Shyamalan
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Episode 40
Daisy Ridley, Tom Hiddleston, Michael Eric Dyson, Noah Cyrus, Leon Bridges
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Episode 41
Bernie Sanders, Katherin Langford, Gary Vaynerchuk
- Episode 42 John Boyega, Abigail Spencer, JP Saxe ft. Julia Michaels
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Episode 43
Tracy Morgan, Brian Regan, Jason Aldean
- Episode 44 Tiffany Haddish, Lakeith Stanfield, The Free Nationals ft. Anderson .Paak
- Episode 45 John Mulaney, Karlie Kloss, Solange
- Episode 46 Kevin Delaney, Felicity Jones, Tomi Adeyemi, Burna Boy
- Episode 47 John Mulaney, Karlie Kloss, Solange
- Episode 48 Jennifer Lopez, Camila Cabello
- Episode 49 Timothée Chalamet, Ashley Graham, Bong Joon Ho, Summer Walker
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Episode 50
Hasan Minhaj, Charlie Puth
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Episode 51
Jon Hamm, Keri Russell, Gary Clark Jr.
- Episode 52 Ryan Reynolds, Niall Horan, Camila Cabello, DaBaby
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Episode 53
Michael B. Jordan, Sam Heughan, Lea Michele ft. Jonathan Groff
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Episode 54
John Lithgow, Liam Payne
- Episode 55 Helen Hunt & Paul Reiser, Dua Lipa, James Blake
- Episode 56 Kate McKinnon, Noah Baumbach, Dua Lipa
- Episode 57 Eddie Murphy, Greta Gerwig, Orlando Leyba
- Episode 58 Shaquille O’Neal, Jacqueline Novak, Lil Baby
- Episode 59 Salma Hayek, George MacKay, Ask This Old House
- Episode 60 Quentin Tarantino, Jodie Whittaker, Nathaniel Rateliff
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Episode 61
Will Smith, Patti Smith
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Episode 62
Martin Lawrence, Matthew Lopez, Kyle Soller, Karol G
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Episode 63
Selena Gomez, Charlie Hunnam, Stormzy
- Episode 64 Tyler Perry, Yara Shahidi, Black Pumas
- Episode 65 Episode 65
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Episode 66
The Cast of Schitt’s Creek, Finn Wolfhard, Justin Willman
- Episode 67 Matthew McConaughey & Hugh Grant, Vanessa Hudgens, Ashley McBryde Jimmy welcomes actors Matthew McConaughey & Hugh Grant, actress Vanessa Hudgens, and a musical performance by Ashley McBryde.
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Episode 68
Ken Jeong, Kate Upton, Old Dominion
Featuring guests Liam Payne; John Lithgow; and more.
- Episode 69 Martin Short, David Dobrik, Yola
- Episode 70 Halsey, Leslie Jones, Claire Saffitz
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Episode 71
Noah Centineo, Wendy Williams, Griselda
- Episode 72 Milo Ventimiglia, Guy Raz, Carmen Lynch
- Episode 73 Michael Strahan, Matt Bomer, Nick Thune
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Episode 74
Michael Bloomberg, Deepak Chopra, Rapsody ft. PJ Morton
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Episode 75
Blake Lively, Jameela Jamil, Roddy Ricch
- Episode 76 J. J. Watt, Louis Tomlinson
- Episode 77 Ewan McGregor, Fran Lebowitz, Mustard & Roddy Ricch
- Episode 78 Andy Samberg, Mary Elizabeth Winstead, Finneas
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Episode 79
Margot Robbie, Jeff Probst, Mura Masa & slowthai
- Episode 80 Claire Danes, Lana Condor, Lil Wayne
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Episode 81
RuPaul, Meghan Trainor
- Episode 82 Jennifer Lopez, Lil Rel Howery, Andre D Thompson
- Episode 83 Janet Jackson, Jane Levy, Jo Firestone
- Episode 84 Constance Wu, Backstreet Boys, Skip Marley & H.E.R.
- Episode 85 Ryan Seacrest, Zoë Kravitz, Jack Harlow
- Episode 86 Rosario Dawson, Logan Lerman, Megan Thee Stallion
- Episode 87 Steve Buscemi, Zoey Deutch, Justin Bieber & Quavo
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Episode 88
BTS: Subway Special
The Tonight Show Starring Jimmy Fallon. The Tonight Show Takes Over New York City's Subway with BTS!
- Episode 89 Nick Jonas, Steve Coogan, “Girl from the North Country”
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Episode 90
David Beckham, Guy Fieri, Doja Cat
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Episode 91
John Mulaney, Bad Bunny
- Episode 92 Norman Reedus, Hailey Bieber, A Boogie Wit Da Hoodie
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Episode 93
Rachel Maddow, Pamela Adlon, Joji
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Episode 94
Kevin Bacon, Tan France, Taylor Tomlinson
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Episode 95
Hillary Rodham Clinton, Noah Schnapp, Jane Birkin, Iggy Pop
- Episode 96 Seth Meyers, Whitney Cummings, Puss N Boots
- Episode 97 Carrie Underwood, Diego Luna, Lauv
- Episode 98 Alex Rodriguez, KJ Apa, HAIM
- Episode 99 Nick Offerman, Charli D’Amelio, HAIM
- Episode 100 Senator Bernie Sanders, Angela Bassett, Isabel Hagen
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Episode 101
Dr. Oz, Mandy Moore, Dane DeHaan
- Episode 102 At Home Edition: The First One
- Episode 103 Lin-Manuel Miranda
- Episode 104 Jennifer Garner
- Episode 105 J Balvin
- Episode 106 At Home Edition: Trevor Noah, DJ D-Nice
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Episode 107
At Home Edition: John Legend
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Episode 108
At Home Edition: Niall Horan
Former professional soccer player David Beckham; chef Guy Fieri; Doja Cat performs.
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Episode 109
At Home Edition: Alec Baldwin, 5 Seconds of Summer
- Episode 110 At Home Edition: Tina Fey, Jose Andres
- Episode 111 At Home Edition: Kim Kardashian West, Jon Bon Jovi, Ryan Tedder
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Episode 112
At Home Edition: Demi Lovato, Jonathan Van Ness
- Episode 113 At Home Edition: Vice President Joe Biden, Andy Puddicombe, Marcus Mumford
- Episode 114 At Home Edition: Adam Sandler, Jessica Alba, Hot Country Knights
- Episode 115 At Home Edition: Miley Cyrus, Rachel Brosnahan, Lewis Capaldi
- Episode 116 At Home Edition: Lady Gaga, Andy Cohen, Billie Joe Armstrong
- Episode 117 At Home Edition: Justin Timberlake, Russell Wilson & Ciara, The Avett Brothers
- Episode 118 At Home Edition: Taraji P. Henson, Dua Lipa
- Episode 119 At Home Edition: Mike D & Ad-Rock, Anna Kendrick
- Episode 120 At Home Edition: Kerry Washington, Andrew Rannells, Anderson .Paak & The Free Nationals
- Episode 121 At Home Edition: Blake Shelton, Kenan Thompson, Gwen Stefani
- Episode 122 At Home Edition: Michael Shannon, JJ Watt, Rita Ora
- Episode 123 At Home Edition: Pharrell Williams, Millie Bobby Brown
- Episode 124 At Home Edition: Chelsea Handler, Kelly Clarkson, Michael McDonald
- Episode 125 At Home Edition: Hugh Jackman, Rose Byrne, Kesha
- Episode 126 At Home Edition: Melissa McCarthy & Octavia Spencer, Megan Thee Stallion, Dan White
- Episode 127 At Home Edition: Halle Berry, Russell Westbrook, Meghan Trainor
- Episode 128 At Home Edition: LL Cool J, Dr. Jane Goodall, Kate Tempest
- Episode 129 At Home Edition: Alex Rodriguez, Rhett & Link, Tones and I
- Episode 130 At Home Edition: Jonas Brothers, Lester Holt, Charli D’Amelio, Chvrches
- Episode 131 At Home Edition: Kate Hudson, Alessia Cara
- Episode 132 At Home Edition: Ricky Gervais, Billy Porter, The Lumineers
- Episode 133 At Home Edition: Shailene Woodley, Maluma, Thom Yorke
- Episode 134 At Home Edition: Vince Vaughn, Gigi Hadid, Maluma
- Episode 135 At Home Edition: Jon Hamm, Brene Brown, Will Ferrell, Kristen Wiig, Jake Gyllenaal, Hailee Steinfeld
- Episode 136 At Home Edition: Ashton Kutcher, Mila Kunis, Evan Rachel Wood, Annie Lennox
- Episode 137 At Home Edition: Ryan Reynolds, Karlie Kloss, Ezra Koenig
- Episode 138 At Home Edition: Gov. Andrew Cuomo, Gabrielle Union, Brad Paisley At Home Edition: Ethan Hawke, Elle Fanning and musical guest Kane Brown.
- Episode 139 At Home Edition: Queen Latifah, Pete Davidson, Judd Apatow, James Taylor
- Episode 140 At Home Edition: Mark Ruffalo, Bill Murray & Guy Fieri, Miranda Lambert
- Episode 141 At Home Edition: Seth MacFarlane, David Chang, Lady Antebellum
- Episode 142 At Home Edition: Ethan Hawke, Elle Fanning, Maroon 5 At Home Edition: Cole Sprouse and musical guest Billy Corgan.
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Episode 143
At Home Edition: David Spade, Kathryn Hahn, Horatio Sanz, The Killers
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Episode 144
At Home Edition: Chris Evans, Mo Willems, Kane Brown
- Episode 145 At Home Edition: Dwayne Johnson, Daveed Diggs, The Head and The Heart
- Episode 146 At Home Edition: Arnold Schwarzenegger, Cole Sprouse, Billy Corgan
- Episode 147 At Home Edition: Ben Stiller, Hannah Gadsby, Tim McGraw
- Episode 148 At Home Edition: Anthony Anderson, Michelle Dockery, Gary Clark Jr.
- Episode 149 At Home Edition: Sofia Vergara, Steve Coogan & Rob Brydon, Courtney Barnett
- Episode 150 At Home Edition: Jennifer Lopez, Henry Winkler, Twenty One Pilots
- Episode 151 At Home Edition: Derrick Johnson, Don Lemon, Jane Elliott, The Roots and Bilal At Home Edition: Derrick Johnson, Don Lemon, Jane Elliott, The Roots and Bilal
- Episode 152 At Home Edition: Kareem Abdul-Jabbar, Phoebe Robinson, W. Kamau Bell
- Episode 153 At Home Edition: Senator Kamala Harris, Talib Kweli, Roy Wood Jr, The Roots & Yim Yames
- Episode 154 At Home Edition: Senator Bernie Sanders, Dr. Bernice A. King, Wyatt Cenac
- Episode 155 At Home Edition: John Oliver, Spike Lee, Benee ft. Gus Dapperton
- Episode 156 At Home Edition: Queer Eye’s Fab Five, Christian Slater, Sia
- Episode 157 At Home Edition: Robert De Niro, James Blake, Lenny Kravitz
- Episode 158 At Home Edition: Anthony Mackie, David Dobrik, Avril Lavigne
- Episode 159 At Home Edition: Kevin Bacon, Aunjanue Ellis, Sarah Cooper, Christine and the Queens
- Episode 160 At Home Edition: Martin Short, Bashir Salahuddin & Diallo Riddle, Randy Newman
- Episode 161 At Home Edition: Gwyneth Paltrow, Zachary Quinto, Alec Benjamin
- Episode 162 At Home Edition: Sean Penn, Robin DiAngelo, Weezer
- Episode 163 At Home Edition: Don Cheadle, Reverend Al Sharpton, Luke Bryan
- Episode 164 At Home Edition: John Legend, Mike Birbiglia
- Episode 165 At Home Edition: Lin-Manuel Miranda, Kenya Barris, Michael Stipe & Big Red Machine
- Episode 166 At Home Edition: Russell Crowe, Ben Platt, Brittany Howard
- Episode 167 At Home Edition: Shaquille O’Neal, John Lithgow, Ozuna
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Episode 168
At Home Edition: Pierce Brosnan, Nicole Richie, Blackpink
Jimmy invites Pierce Brosnan, Nicole Richie and Blackpink to #FallonAtHome for another social distancing home edition of The Tonight Show.
- Episode 169 At Home Edition: Charlize Theron, Gov. Andrew Cuomo, Little Big Town
- Episode 170 At Home Edition: Colin Jost, Rep. Val Demings, Davido
- Episode 171 James McAvoy, Stacey Abrams, My Morning Jacket
- Episode 172 Jim Carrey, Jenny Slate, Luke Combs
- Episode 173 David Schwimmer, Alison Brie, Jimmy Buffett
- Episode 174 Andy Samberg, Jose Andres, Perfume Genius
- Episode 175 Cameron Diaz, Mayor Keisha Lance Bottoms, Kygo with OneRepublic
- Episode 176 Will Arnett, Michaela Coel, H.E.R.
- Episode 177 Mike Tyson, Adam Devine, Chronixx
- Episode 178 Michael Che, Megan Rapinoe, Angel Olsen
- Episode 179 Ice T, Jack Whitehall, Charlie Wilson
- Episode 180 Seth Rogen, Chiwetel Ejiofor, Alanis Morissette
- Episode 181 Common, Matisse Thybulle, Rufus Wainwright
- Episode 182 Jesse Eisenberg, Blake Griffin, Gracie Abrams
- Episode 183 Jamie Foxx, Tig Notaro, Black Pumas
- Episode 184 Matthew McCounaughey, Jaden Smith
- Episode 185 Bryan Cranston, Julia Garner, Surfaces
- Episode 186 Orlando Bloom, Cecily Strong, Trey Anastasio
- Episode 187 Joseph Gordon-Levitt/Paula Pell/Jessie Reyez Actor Joseph Gordon-Levitt ("Project Power" and "Knives Out"); actress Paula Pell ("Mapleworth Murders"); Jessie Reyez performs;
- Episode 188 Seth Meyers, David Blaine, Burna Boy
- Episode 189 Tiffany Haddish, Jurnee Smollett, Orville Peck & Shania Twain
- Episode 190 Hugh Jackman. Lili Reinhart, Buju Banton
- Episode 191 Tyler Perry, Maisie Williams, Trevor Daniel
- Episode 192 Rachel Maddow, Fred Armisen, Tiwa Savage
- Episode 193 Joel McHale, Big Sean
- Episode 194 Kevin Hart, Josh Charles, CHIKA
- Episode 195 Miley Cyrus
- Episode 196 Kelly Clarkson, Joy Reid, The Flaming Lips
- Episode 197 Jude Law, Maya Erskine and Anna Konkle, Summer Walker
- Episode 198 Ewan McGregor, Willie and Bobbie Nelson, Kesha
- Episode 199 Sharon Stone, Shaquille O’Neal, Kylie Minogue
- Episode 200 Seth MacFarlane, Evan Rachel Wood
- Episode 201 Jessica Alba, Jack Huston, Keith Urban