Watch Demo
  1. Episode 1 Neil Patrick Harris / Karen Fisher / Nickel Creek September 12, 2005, 1 h
  2. Episode 2 Bruce Campbell / Melinda Clarke / Flight of the Conchords September 13, 2005, 1 h Shannen Doherty; Eddie Kaye Thomas; E-40; T-Pain.
  3. Episode 3 Patricia Arquette / Connie Schultz / Paul Weller September 14, 2005, 1 h
  4. Episode 4 Carla Gugino / Alice Cooper September 15, 2005, 1 h
  5. Episode 5 Alyson Hannigan / Steve Jones September 16, 2005, 1 h
  6. Episode 6 Cybill Shepherd / Phil Keoghan / Institute September 19, 2005, 1 h
  7. Episode 7 Tyra Banks / Tyler James Williams / Ted Alexandro September 20, 2005, 1 h
  8. Episode 8 Nick Cannon / Jeff Probst / Lawrence Turman September 21, 2005, 1 h
  9. Episode 9 Aisha Tyler / Seth MacFarlane / Thirty Seconds to Mars September 22, 2005, 1 h
  10. Episode 10 Susan Sarandon / Tom Everett Scott / INXS September 23, 2005, 1 h
  11. Episode 11 Danny Bonaduce / Diane Farr / Shaggy September 26, 2005, 1 h
  12. Episode 12 Maria Bello / Jason Segel September 27, 2005, 1 h
  13. Episode 13 Alan Alda / Jennifer Coolidge September 28, 2005, 1 h
  14. Episode 14 Fran Drescher / Robert David Hall / Jo Dee Messina September 29, 2005, 1 h
  15. Episode 15 Toni Collette / Dave Price / Robert Plant & Strange Sensation September 30, 2005, 1 h
  16. Episode 16 Julian McMahon / Jennifer Finnigan October 3, 2005, 1 h
  17. Episode 17 Taryn Manning / Dr. Drew / Butch Bradley October 4, 2005, 1 h
  18. Episode 18 David Duchovny / Sinéad O’Connor October 5, 2005, 1 h
  19. Episode 19 Henry Winkler / Aron Ralston / Julie Gribble October 6, 2005, 1 h
  20. Episode 20 Illeana Douglas / Macy Gray October 7, 2005, 1 h
  21. Episode 21 Macy Gray / Nuala O’Faolain / Rihanna October 10, 2005, 1 h
  22. Episode 22 Dennis Hopper / Cheryl Hines / Sarge October 11, 2005, 1 h
  23. Episode 23 Joe Mantegna / Sue Johanson October 12, 2005, 1 h
  24. Episode 24 Sanjay Gupta / Stephen Collins October 13, 2005, 1 h
  25. Episode 25 Bill Nye / Kevin Bacon & Michael Bacon / Bacon Brothers October 14, 2005, 1 h
  26. Episode 26 Joely Fisher / McG / Switchfoot October 17, 2005, 1 h
  27. Episode 27 Melina Kanakaredes / Stephen Robinson October 18, 2005, 1 h
  28. Episode 28 Betty White / Rhona Mitra / Ray J October 19, 2005, 1 h
  29. Episode 29 Stockard Channing / Michael Connelly / Jamie Cullum October 20, 2005, 1 h
  30. Episode 30 Jason Schwartzman / Mitch Braswell / Paul Weller October 21, 2005, 1 h
  31. Episode 31 Sharon Osbourne October 31, 2005, 1 h
  32. Episode 32 Maria Bartiromo / Jamie Kaler / Clint Black November 1, 2005, 1 h
  33. Episode 33 Anthony LaPaglia / Jeri Ryan November 2, 2005, 1 h
  34. Episode 34 Charlie Sheen / Marissa Jaret Winokur / Franz Ferdinand November 3, 2005, 1 h
  35. Episode 35 Gina Gershon / Rob Zombie / Sinéad O’Connor November 4, 2005, 1 h
  36. Episode 36 Hugh Laurie / Twiggy / Patty Loveless November 7, 2005, 1 h
  37. Episode 37 Brenda Blethyn / Jim Sheridan / John Roy November 8, 2005, 1 h
  38. Episode 38 John Leguizamo / Kara Cooney / My Morning Jacket November 9, 2005, 1 h
  39. Episode 39 John Malkovich November 10, 2005, 1 h
  40. Episode 40 Xzibit / Doug Savant / Buddy Guy November 11, 2005, 1 h
  41. Episode 41 James Belushi / Parminder Nagra / Matisyahu November 14, 2005, 1 h
  42. Episode 42 Patti Smith / John Lahr November 15, 2005, 1 h
  43. Episode 43 Anne Heche / Tom Amandes / Jay Larson November 16, 2005, 1 h
  44. Episode 44 RZA / Josh Schwartz / Amos Lee November 17, 2005, 1 h
  45. Episode 45 Jon Favreau / Randy Cohen / Maz Jobrani November 18, 2005, 1 h
  46. Episode 46 Juliette Lewis / Brian Van Holt November 21, 2005, 1 h
  47. Episode 47 Jerry O’Connell / Joely Richardson / The Fray November 22, 2005, 1 h
  48. Episode 48 Regis Philbin / Maureen Dowd November 23, 2005, 1 h
  49. Episode 49 Jennifer Love Hewitt / James Denton / Robert Plant November 24, 2005, 1 h
  50. Episode 50 Danny Bonaduce / Paul Haggis November 25, 2005, 1 h
  51. Episode 51 Ted Danson / Kristen Bell / Matt Fulchiron November 28, 2005, 1 h
  52. Episode 52 Sela Ward / Lawrence O’Donnell / Chris Botti / Paul Buchanan November 29, 2005, 1 h
  53. Episode 53 Tony Shalhoub / Mitch Albom November 30, 2005, 1 h
  54. Episode 54 Miranda Lambert / Malachy McCourt December 1, 2005, 1 h
  55. Episode 55 Tom Arnold / Helen Fielding / Lifehouse December 2, 2005, 1 h
  56. Episode 56 Jon Cryer / Amy Yasbeck December 12, 2005, 1 h
  57. Episode 57 John Waters / David Steinberg / Nada Surf December 13, 2005, 1 h
  58. Episode 58 Poppy Montgomery / Mancow December 14, 2005, 1 h
  59. Episode 59 Michelle Yeoh / Jeremy Roenick / Trey Anastasio December 15, 2005, 1 h
  60. Episode 60 Chris Isaak / Sara Gilbert / Keaton Simons December 16, 2005, 1 h
  61. Episode 61 Dennis Quaid / Bill Nye / Bob Marley December 19, 2005, 1 h
  62. Episode 62 Dwight Yoakam / Teri Garr December 20, 2005, 1 h
  63. Episode 63 Little Richard / Brian Cox December 21, 2005, 1 h
  64. Episode 64 Téa Leoni / Amy Tan / RZA December 22, 2005, 1 h
  65. Episode 65 Katey Sagal / Colin Hanks / Brian McKnight December 23, 2005, 1 h
  66. Episode 66 Drew Pinsky / Bob Spitz January 2, 2006, 1 h
  67. Episode 67 Fred Willard / Connie Schultz January 3, 2006, 1 h
  68. Episode 68 Rob Morrow / Bob Marley January 4, 2006, 1 h
  69. Episode 69 Don Rickles / Ivana Miličević / Aimee Mann January 5, 2006, 1 h
  70. Episode 70 Daryl Hannah / Thomas Lennon January 6, 2006, 1 h
  71. Episode 71 Cheryl Hines / Derek Luke / Trey Anastasio January 9, 2006, 1 h
  72. Episode 72 Phil McGraw / Sebastian Maniscalco January 10, 2006, 1 h
  73. Episode 73 Seth Green / Peter Bart / Peter Guber January 11, 2006, 1 h
  74. Episode 74 Tom Selleck / Connie Britton / Ian Edwards January 12, 2006, 1 h
  75. Episode 75 Steven Wright / Lola Glaudini / Anthony Hamilton January 13, 2006, 1 h
  76. Episode 76 Allison Janney / John C. McGinley / The 88 January 16, 2006, 1 h
  77. Episode 77 Greg Kinnear / Paula Poundstone / Ming Tsai January 17, 2006, 1 h
  78. Episode 78 Thomas Cavanagh January 18, 2006, 1 h
  79. Episode 79 Vanessa Williams / Rogue Wave January 19, 2006, 1 h
  80. Episode 80 Mimi Rogers / Living Things January 20, 2006, 1 h
  81. Episode 81 Drew Pinsky / Amy Yasbeck / Wicked Tinkers January 30, 2006, 1 h
  82. Episode 82 Jim Belushi / Parminder Nagra / Matisyahu January 31, 2006, 1 h
  83. Episode 83 James Woods / Piper Perabo / Keaton Simons February 1, 2006, 1 h
  84. Episode 84 Emma Thompson / Steve Byrne February 2, 2006, 1 h
  85. Episode 85 Lynn Redgrave / Isaiah Washington / Mutemath February 3, 2006, 1 h
  86. Episode 86 Mary Steenburgen / Big & Rich February 6, 2006, 1 h
  87. Episode 87 Jeff Probst / Lauren Holly / Ne-Yo February 7, 2006, 1 h
  88. Episode 88 Zooey Deschanel / Trace Adkins February 8, 2006, 1 h
  89. Episode 89 Jean Reno / Sanaa Lathan February 9, 2006, 1 h
  90. Episode 90 Eddie Izzard / Patti Hall February 10, 2006, 1 h
  91. Episode 91 Alyson Hannigan / Paul Haggis / Frank Caliendo February 13, 2006, 1 h
  92. Episode 92 Marlee Matlin / Lisa Loeb February 14, 2006, 1 h
  93. Episode 93 Paul Reiser / Judy Greer / Jeff Cesario February 15, 2006, 1 h
  94. Episode 94 Kiefer Sutherland / Amy Adams / Rocco DeLuca and the Burden February 16, 2006, 1 h
  95. Episode 95 Jason Biggs / Fiona Apple February 17, 2006, 1 h
  96. Episode 96 William Shatner / Josh Bernstein / Andrea Bocelli February 20, 2006, 1 h
  97. Episode 97 Carl Reiner / Nadine Velazquez / Robert Hawkins February 21, 2006, 1 h
  98. Episode 98 Carl Edwards / William H. Macy February 22, 2006, 1 h
  99. Episode 99 Samuel L. Jackson / Cokie Roberts / The Lashes February 23, 2006, 1 h
  100. Episode 100 Dolly Parton / Kevin Smith / The Cult February 24, 2006, 1 h
  101. Episode 101 Terrence Howard / Eric Haney February 27, 2006, 1 h
  102. Episode 102 Regis Philbin / Tichina Arnold / Jenny Lewis & the Watson Twins February 28, 2006, 1 h
  103. Episode 103 Roseanne Barr / Wolfgang Puck March 1, 2006, 1 h
  104. Episode 104 Kathy Bates / Idina Menzel / Jeremy Bloom March 2, 2006, 1 h
  105. Episode 105 Milla Jovovich / Peter Travers / All American Rejects March 3, 2006, 1 h
  106. Episode 106 Paul Haggis / Ben Lee / James Blake March 6, 2006, 1 h
  107. Episode 107 Tyra Banks / Jackie Collins / Nathan Sawaya March 7, 2006, 1 h
  108. Episode 108 John Larroquette / Ethan Suplee / Fiona Apple March 8, 2006, 1 h
  109. Episode 109 Wynonna / Emilie de Ravin / D. C. Benny March 9, 2006, 1 h
  110. Episode 110 David Arquette / Cowboy Troy March 10, 2006, 1 h
  111. Episode 111 Stockard Channing / Big & Rich March 20, 2006, 1 h
  112. Episode 112 Rosanne Cash / Howie Mandel March 21, 2006, 1 h
  113. Episode 113 Jason Lee / Julian Sands / David Gray March 22, 2006, 1 h
  114. Episode 114 Joan Cusack / Mary McCormack / The New Cars March 27, 2006, 1 h
  115. Episode 115 Jane Kaczmarek / Tom Fontana / Dan Naturman March 28, 2006, 1 h
  116. Episode 116 John Goodman / Angela Nissel / Alkaline Trio March 29, 2006, 1 h
  117. Episode 117 Frankie Muniz / Annie Duke March 30, 2006, 1 h
  118. Episode 118 Chris Kattan / Mo’Nique / Ozomatli March 31, 2006, 1 h
  119. Episode 119 Mehcad Brooks / Anjelica Huston / Ne-Yo April 3, 2006, 1 h
  120. Episode 120 Rosie O’Donnell / Harry Shearer April 4, 2006, 1 h
  121. Episode 121 Paget Brewster / Sam Elliott / Adam Ferrara April 5, 2006, 1 h
  122. Episode 122 Ben Kingsley / Roselyn Sánchez / UB40 April 6, 2006, 1 h
  123. Episode 123 Kevin Pollak / Mira Sorvino / Train April 7, 2006, 1 h
  124. Episode 124 Christian Finnegan / Chi McBride / Bebe Neuwirth April 10, 2006, 1 h
  125. Episode 125 Carrie Fisher / John Corbett April 11, 2006, 1 h
  126. Episode 126 Carl Hiaasen / Toby Keith April 12, 2006, 1 h
  127. Episode 127 Roger Lay Jr. / Ray Romano / Ken Shamrock April 13, 2006, 1 h
  128. Episode 128 Melina Kanakaredes / Kyle MacLachlan / Shinedown April 14, 2006, 1 h
  129. Episode 129 Dennis Quaid / The Wiggles April 24, 2006, 1 h
  130. Episode 130 Radha Mitchell / Marion Ross / Erin Boheme April 25, 2006, 1 h
  131. Episode 131 Jennifer Finnigan / Barry Sonnenfeld April 26, 2006, 1 h
  132. Episode 132 Dave Barry / Dem Franchize Boyz April 27, 2006, 1 h
  133. Episode 133 Kristin Chenoweth / Andy García / Mandy Moore / Rock Bottom Remainders April 28, 2006, 1 h
  134. Episode 134 Neil Patrick Harris / Parminder Nagra / The BellRays May 1, 2006, 1 h
  135. Episode 135 Randy Jackson / Connie Schultz May 2, 2006, 1 h
  136. Episode 136 Reggie Bush / Jennifer Love Hewitt / Frank McCourt / Secret Machines May 3, 2006, 1 h
  137. Episode 137 Emily Deschanel / Kelsey Grammer / Aisha Tyler / The Go! Team May 4, 2006, 1 h
  138. Episode 138 Julia Louis-Dreyfus / Ying-Yang Twins May 5, 2006, 1 h
  139. Episode 139 Denis Leary / Bo Bice May 8, 2006, 1 h
  140. Episode 140 Donald Faison / Betty White / Bill Bailey May 9, 2006, 1 h
  141. Episode 141 Bill Carter / Jenna Fischer / Chris Isaak May 10, 2006, 1 h
  142. Episode 142 Paul Bettany / Kate Walsh / Damian Marley May 11, 2006, 1 h
  143. Episode 143 Jacinda Barrett / Mark Harmon / Rock Kills Kid May 12, 2006, 1 h
  144. Episode 144 Daryl Hannah / Sara Ramirez May 15, 2006, 1 h
  145. Episode 145 Phil McGraw / Jim Gaffigan May 16, 2006, 1 h
  146. Episode 146 Merv Griffin / Rick Reilly May 17, 2006, 1 h
  147. Episode 147 Diane Farr / Dominic Monaghan / Phil Vassar May 18, 2006, 1 h
  148. Episode 148 Mía Maestro / Nick Lachey May 19, 2006, 1 h
  149. Episode 149 Reba McEntire / Cynthia Watros / Toby Keith May 22, 2006, 1 h
  150. Episode 150 Anna Paquin / Casper Van Dien / Jason Aldean May 23, 2006, 1 h
  151. Episode 151 Ricki Lake / Oscar De La Hoya / The Wreckers May 24, 2006, 1 h
  152. Episode 152 Pauley Perrette / Brooks and Dunn May 25, 2006, 1 h
  153. Episode 153 Jenny McCarthy / Jim Short / Gomez May 26, 2006, 1 h
  154. Episode 154 Jon Favreau / Shooter Jennings / Lee Child June 5, 2006, 1 h
  155. Episode 155 Patricia Heaton / Claire Fordham / The New Cars June 6, 2006, 1 h
  156. Episode 156 Ian McShane / Joey Lauren Adams / Stanley Bing June 7, 2006, 1 h
  157. Episode 157 Edie Falco / David Lee Roth June 8, 2006, 1 h
  158. Episode 158 Tom Everett Scott / Ludacris / Speech June 9, 2006, 1 h
  159. Episode 159 Sara Rue / Anthony Michael Hall / Secret Machines June 12, 2006, 1 h
  160. Episode 160 Anderson Cooper / Mercedes Ruehl / Dan Cummins June 13, 2006, 1 h
  161. Episode 161 Lorraine Bracco / Kevin Connolly / Jamie Jenson June 14, 2006, 1 h
  162. Episode 162 Tony Shalhoub / Lucy Davis / Echo & the Bunnymen June 15, 2006, 1 h
  163. Episode 163 Jon Cryer / Jim Short / Three Days Grace June 16, 2006, 1 h
  164. Episode 164 Pepe the King Prawn / Sarah Wynter / The Charlatans June 19, 2006, 1 h
  165. Episode 165 Katey Sagal / David Milch / Arturo Gatti June 20, 2006, 1 h
  166. Episode 166 Stanley Tucci / Cat Deeley / Van Hunt June 21, 2006, 1 h
  167. Episode 167 Jack Black / James Marsden / Sonya Kitchell June 22, 2006, 1 h
  168. Episode 168 Tyrese Gibson / Def Leppard / Paul Morrissey June 23, 2006, 1 h
  169. Episode 169 Regis Philbin / John Landis / Snoop Dogg June 26, 2006, 1 h
  170. Episode 170 Henry Winkler / Judy Greer / Mike Young June 27, 2006, 1 h
  171. Episode 171 Dave Foley / Amy Sedaris / UB40 June 28, 2006, 1 h
  172. Episode 172 Tim Robbins / T.I. June 29, 2006, 1 h
  173. Episode 173 Jesse James / Paul Dinello / She Wants Revenge June 30, 2006, 1 h
  174. Episode 174 Laurence Fishburne / Illeana Douglas, / Jack’s Mannequin July 5, 2006, 1 h
  175. Episode 175 Tom Lennon / Jewel July 6, 2006, 1 h
  176. Episode 176 Donal Logue / Ne-Yo July 7, 2006, 1 h
  177. Episode 177 Toni Collette / Lawrence Block / Joe Theismann July 10, 2006, 1 h
  178. Episode 178 Julie Chen / Denise Mina / Echo & the Bunnymen July 11, 2006, 1 h
  179. Episode 179 Danny Bonaduce / Cote De Pablo / Bill McArthur July 12, 2006, 1 h
  180. Episode 180 Joe Mantegna / Brooks & Dunn July 13, 2006, 1 h
  181. Episode 181 Nick Cannon / Kyle Dunnigan / Family Force 5 July 14, 2006, 1 h
  182. Episode 182 Eddie Izzard / Greg Warren / The Buzzcocks July 24, 2006, 1 h
  183. Episode 183 Kevin Smith / Carrie Ann Inaba / Seether July 25, 2006, 1 h
  184. Episode 184 Cuba Gooding Jr. / Jay Larson / Jurassic 5 July 26, 2006, 1 h
  185. Episode 185 Greg Kinnear / Hugh Hefner / Sammy Hagar July 27, 2006, 1 h
  186. Episode 186 Kyra Sedgwick / Keith Olbermann July 28, 2006, 1 h
  187. Episode 187 Andie MacDowell / Cirque du Soleil’s KA July 31, 2006, 1 h
  188. Episode 188 Bonnie Raitt / Travis Pastrana / Randy Kagan August 1, 2006, 1 h
  189. Episode 189 Drew Pinsky / Carnie Wilson / Tally Hall August 2, 2006, 1 h Tally Hall performs "Good Day" during their national TV debut on The Late, Late Show w/ Craig Ferguson (CBS) on August 02, 2006.
  190. Episode 190 Jaime Pressly / Robbie Coltrane / Michael Franti & Spearhead August 3, 2006, 1 h
  191. Episode 191 Carlos Mencia / Natasha Bedingfield August 4, 2006, 1 h
  192. Episode 192 Steve Carell / The Subways August 7, 2006, 1 h
  193. Episode 193 Aaron Eckhart / Cheyenne Kimball / Fran Solomita August 8, 2006, 1 h
  194. Episode 194 Tim Olyphant / Lindsay Sloane / The Editors August 9, 2006, 1 h
  195. Episode 195 Christina Milian / Tim Olyphant / Brian Malow August 10, 2006, 1 h
  196. Episode 196 Michael Clarke Duncan / Laura Kightlinger / Rob Zombie August 11, 2006, 1 h
  197. Episode 197 Chi McBride / Lili Taylor / Nick Lachey August 14, 2006, 1 h
  198. Episode 198 Matt Dillon / Padma Lakshmi / Paula DeAnda / Baby BashMatt Dillon / Padma Lakshmi / Paula DeAnda / Baby Bash August 15, 2006, 1 h
  199. Episode 199 Alice Cooper / Penelope Ann Miller August 16, 2006, 1 h
  200. Episode 200 Jane Kaczmarek / Esai Morales / Larke Miller August 17, 2006, 1 h
  201. Episode 201 Shannen Doherty / Eddie Kaye Thomas / E-40 T-Pain August 21, 2006, 1 h
  202. Episode 202 Fred Willard / Rachel Blanchard / Stephen J. Cannell August 22, 2006, 1 h
  203. Episode 203 Amy Smart / Trace Adkins August 23, 2006, 1 h
  204. Episode 204 Denis Leary / Lewis Dix / Matt Goss August 24, 2006, 1 h
  205. Episode 205 André Benjamin / David Boreanaz / Mellowdrone August 25, 2006, 1 h