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The CSI team unravels a string of complex murders while racing to identify a serial killer whose diabolical medical skills confound the experts.

  1. Family Affair Episode 1 Family Affair September 24, 2009, 45 min A rising young star is killed in a wreck and her determined stalker claims credit, but the team finds out there's more to this tragedy than meets the eye.
  2. Ghost Town Episode 2 Ghost Town October 1, 2009, 45 min The son of a notorious killer is arrested on suspicion of murder, and the CSI team must overcome their natural prejudices against the boy's antecedents in order to track the…
  3. Working Stiffs Episode 3 Working Stiffs October 8, 2009, 45 min The team investigates the murder of Jason, a troubled computer geek working at a low-level casino support industry job who lures a colleague, Paulie, into a dangerous plan to make…
  4. Coup de Grace Episode 4 Coup de Grace October 15, 2009, 44 min When a policeman kills another officer, the CSIs must look to the evidence to determine if the shooting was premeditated or an accident.
  5. Bloodsport Episode 5 Bloodsport October 29, 2009, 45 min After a beloved college football coach is found dead and his house drenched and spattered with his blood, the CSI team hunts for the killer who didn't find Coach Jimmy…
  6. Death and the Maiden Episode 6 Death and the Maiden November 5, 2009, 44 min When two seemingly different crimes turn out to be related, the CSIs discover they're interlocking parts of the same revenge plot.
  7. The Lost Girls (III) Episode 7 The Lost Girls (III) November 12, 2009, 45 min The CSI team helps Ray Langston investigate a prostitution ring that may have harbored a hostage he has been looking for in Miami and New York. The crossover starts on…
  8. Lover’s Lanes Episode 8 Lover’s Lanes November 19, 2009, 45 min A bowling tournament is disrupted when an important piece of evidence is uncovered, leading the CSIs to investigate a murder at the same bowling alley.
  9. Appendicitement Episode 9 Appendicitement December 10, 2009, 45 min When Nick, Greg and Hodges take Henry to celebrate his birthday at a biker bar, they uncover a double homicide and find several suspects still at the bar who may…
  10. Better Off Dead Episode 10 Better Off Dead December 17, 2009, 43 min The CSIs dig to find the truth about how a recent shootout at a gun store might connect to a young woman who may have committed suicide.
  11. Sin City Blue Episode 11 Sin City Blue January 14, 2010, 45 min Two secretaries on holiday from Arizona attempt to steal a man's wallet and ATM pin number in a scam, and wind up dead in different locations. Meanwhile, the CSI team…
  12. Long Ball Episode 12 Long Ball January 21, 2010, 44 min The CSI investigates the mystifying death of a former pro golfer whose allegiance to the game might have cost him everything.
  13. Internal Combustion Episode 13 Internal Combustion February 4, 2010, 43 min The case of two high school students, one dead and one missing, lead the CSIs into the underbelly of streetcar racing and a tangled web of deadly competition.
  14. Unshockable Episode 14 Unshockable March 4, 2010, 45 min When a band member of Rascal Flatts is electrocuted by his own guitar during a concert, the CSI team investigates if it was a case of foul play.
  15. Neverland Episode 15 Neverland March 11, 2010, 44 min When a young boy is found murdered, the CSI team uncovers evidence that may link his death to an old case that recently resurfaced.
  16. The Panty Sniffer Episode 16 The Panty Sniffer April 1, 2010, 45 min Catherine and Detective Vartann are thrown together in a hotel room for 24 hours as they stake out a duo making drugs in the room next door. Meanwhile, Nick and…
  17. Irradiator Episode 17 Irradiator April 8, 2010, 45 min When the CSI team investigates the brutal murder of a family, they trace the killer to the house next door, which might belong to the "Dr. Jekyll" serial killer.
  18. Field Mice Episode 18 Field Mice April 15, 2010, 45 min When Hodges and Wendy take a group of high school CSI Explorer Scouts on a field trip, they embellish their role in solving cases and take their assignment a little…
  19. World’s End Episode 19 World’s End April 22, 2010, 44 min When a student is discovered murdered at Lindsey's school, the investigation takes a sharp turn when the CSIs uncover an unlikely connection between the boy's death and atrocities of the…
  20. Take My Life, Please! Episode 20 Take My Life, Please! April 29, 2010, 44 min A legendary comic from the good old days of Las Vegas is set to reunite with his partner on stage for one night only, until one half of the famous…
  21. Lost & Found Episode 21 Lost & Found May 6, 2010, 43 min A mother thought to be grieving for the loss of her family three years ago becomes a suspect in a CSI investigation.
  22. Doctor Who Episode 22 Doctor Who May 13, 2010, 43 min The CSI team must investigate one of their own when Langston is accused by a former colleague of being part of the Dr. Jekyll murders, on part one of a…
  23. Meat Jekyll Episode 23 Meat Jekyll May 20, 2010, 45 min The CSI's lives are on the line as they close in on the elusive Dr. Jekyll, and more than one member of the team may not live to see his…